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805988-overview

It works by changing the effects of chemicals in the brain.

Other inhibitors of CYP3A4 would be expected to have similar effects.Cimetidine at a dose of 800 mg QD for 2 days did not affect ziprasidone pharmacokinetics.Ziprasidone at a dose of 40 mg twice daily administered concomitantly with A pharmacokinetic interaction of ziprasidone with valproate is unlikely due to the lack of common metabolic pathways for the two drugs. All trials were in adult inpatients, most of whom met Several instruments were used for assessing psychiatric signs and symptoms in these studies. They are supplied in the following strengths and package configurations:GEODON for Injection is available in a single-dose vial as ziprasidone mesylate (20 mg ziprasidone/mL when reconstituted according to label instructions) [see GEODON Capsules are differentiated by capsule color/size and are imprinted in black ink with “Pfizer and ZDX [dosage strength]” or with “Pfizer” and a unique number. Signs of DRESS may include rash, fever, and swollen lymph nodes.

Skip the missed dose if it is almost time for your next scheduled dose. When deciding among the alternative treatments available for the condition needing treatment, the prescriber should consider the finding of ziprasidone’s greater capacity to prolong the QT/QTc interval compared to several other antipsychotic drugs [see GEODON Capsules should be administered at an initial daily dose of 20 mg twice daily with food.

However, the syndrome can develop, although much less commonly, after relatively brief treatment periods at low doses.There is no known treatment for established cases of tardive dyskinesia, although the syndrome may remit, partially or completely, if antipsychotic treatment is withdrawn.

Avoid driving or operating machinery until you know how this medicine will affect you. and formulary information changes.

Call your doctor for medical advice about side effects. This product may contain inactive ingredients, which can cause allergic reactions or other problems. These side effects may diminish over time as your body gets used to daily treatment with propranolol 1 2.

Other severe cutaneous adverse reactions (SCAR), such as Stevens-Johnson syndrome can occur with ziprasidone. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Signs of DRESS may include rash, fever, and swollen lymph nodes.

GEODON is a prescription medicine and only your doctor can decide if it is right for you. The safety of doses above 100 mg twice daily has not been systematically evaluated in clinical trials [see While there is no body of evidence available to answer the question of how long a patient treated with ziprasidone should remain on it, a maintenance study in patients who had been symptomatically stable and then randomized to continue ziprasidone or switch to placebo demonstrated a delay in time to relapse for patients receiving GEODON [see Dose Selection-Oral ziprasidone should be administered at an initial daily dose of 40 mg twice daily with food.

Ask your doctor or pharmacist if you do not understand any of this information or if you want to know more about GEODON.GEODON is a type of prescription medicine called a psychotropic, also known as an atypical antipsychotic.

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In the second phase of the trial, ECGs were obtained at the time of maximum plasma concentration while the drug was co-administered with an inhibitor of the CYP4503A4 metabolism of the drug.In the first phase of the study, the mean change in QTc from baseline was calculated for each drug, using a sample-based correction that removes the effect of heart rate on the QT interval.

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